Alprazolam is a class of prescription medications called Benzodiazepines which act on the brain and central nervous system to produce the calming effect. Learn more about Alprazolam use, mechanism of actions, side effects, dose etc.

PREGNANCY CATEGORY 

  D

THERAPEUTIC CLASS 

Benzodiazepine Sedatives, Anxiolytic Drug

INDICATIONS

  • Anxiety disorder
  • Generalized anxiety disorder
  • Panic disorder with or without agoraphobia

PHARMACOLOGY

  • Bind non specifically to benzodiazepine receptors BNZ1 & BNZ2
  • Coupled to GABA receptor
  • Increasing affinity for the GABA receptor
  • Hyperpolarization of the cell membrane
  • Prevent excitation of the cell

DOSAGE & ADMINISTRATION

  •  Adult Dose: 0.25 mg 2 or 3 times per day
  • For elderly and debilitated patient : 0.125 mg 2 or 3 times per day.

INTERACTIONS

  • Other Psychotropic medications
  • Anticonvulsant
  • Antihistamine
  • Antifungals
  • Macrolide antibiotics
  • Alcohol & Cigarette smoking

CONTRAINDICATIONS

  • Hypersensitivity to alprazolam or other benzodiazepines
  • Myasthenia gravis
  • Acute Narrow angle glaucoma
  • Pregnancy
  • Infants

SIDE EFFECTS

  • Saliva production increases
  • Irritability, excitability and hallucinations
  • Drowsiness
  • Dizziness
  • Loss of coordination
  • Serious allergic reactions is rarely occur

STORAGE

  • Stored in a cool and dry Place
  • Protected from light and moisture

DOSAGE FORM & STRENGTH AVAILABLE IN THE MARKET

  • Tablet – 0.25 mg, 0.5 mg
  • Tablet ER –  1mg
  • Tablet SR –  1mg

 

 

Share.

About Author

Leave A Reply